Mercedes-Benz

E350

Midsize Cars · model years 2006 to 2026

Includes E350, E350 4matic, E350 4matic (wagon) and 3 more as listed by the EPA.

See all 84 E350 trims All Mercedes-Benz cars

The verdict

Best year: 2025. complaints: 0, this model typically has none on file; recalls: 0, this model typically has none on file.

Worst year: 2010. complaints: 0, this model typically has none on file; recalls: 0, this model typically has none on file.

Year by year

Year by year summary for the Mercedes-Benz E350
Year	Trims	MPG	Fuel cost	Recalls	Complaints	Investigations	TSBs
2006	3Gas	19	$4,050	no data	no data	0	no data
no complaint or recall data on file for 2006
2007	3Gas	19	$4,050	no data	no data	0	no data
no complaint or recall data on file for 2007
2008	3Gas	18	$4,300	no data	no data	0	no data
no complaint or recall data on file for 2008
2009	3Gas	18	$4,300	no data	no data	0	no data
no complaint or recall data on file for 2009
2010	3Gas	20	$3,850	0	0	2 (1 open)	159
complaints: 0, this model typically has none on file recalls: 0, this model typically has none on file open NHTSA investigations: 1 Score: 87 of 100, where higher is better.
2011	5Gas	20	$3,850	0	0	2 (1 open)	120
complaints: 0, this model typically has none on file recalls: 0, this model typically has none on file open NHTSA investigations: 1 Score: 87 of 100, where higher is better.
2012	9Gas	22	$3,500	0	0	2 (1 open)	125
complaints: 0, this model typically has none on file recalls: 0, this model typically has none on file open NHTSA investigations: 1 Score: 87 of 100, where higher is better.
2013	15Gas	22	$3,500	0	0	2 (1 open)	128
complaints: 0, this model typically has none on file recalls: 0, this model typically has none on file open NHTSA investigations: 1 Score: 87 of 100, where higher is better.
2014	15Gas	23	$3,350	0	0	2 (1 open)	112
complaints: 0, this model typically has none on file recalls: 0, this model typically has none on file open NHTSA investigations: 1 Score: 87 of 100, where higher is better.
2015	7Gas	23	$3,350	0	0	2 (1 open)	106
complaints: 0, this model typically has none on file recalls: 0, this model typically has none on file open NHTSA investigations: 1 Score: 87 of 100, where higher is better.
2016	5Gas	23	$3,350	0	0	1 (1 open)	104
complaints: 0, this model typically has none on file recalls: 0, this model typically has none on file open NHTSA investigations: 1 Score: 87 of 100, where higher is better.
2020	2Gas	25.5	$3,025	0	0	0	no data
complaints: 0, this model typically has none on file recalls: 0, this model typically has none on file Score: 95 of 100, where higher is better.
2021	2Gas	25	$3,100	0	0	0	no data
complaints: 0, this model typically has none on file recalls: 0, this model typically has none on file Score: 95 of 100, where higher is better.
2022	2Gas	25	$3,075	0	0	0	no data
complaints: 0, this model typically has none on file recalls: 0, this model typically has none on file Score: 95 of 100, where higher is better.
2023	2Gas	25	$3,075	0	0	0	no data
complaints: 0, this model typically has none on file recalls: 0, this model typically has none on file Score: 95 of 100, where higher is better.
2024	1Hybrid	27	$2,850	0	0	0	no data
complaints: 0, this model typically has none on file recalls: 0, this model typically has none on file Score: 95 of 100, where higher is better.
2025	2Hybrid	27.5	$2,700	0	0	0	no data
complaints: 0, this model typically has none on file recalls: 0, this model typically has none on file Score: 95 of 100, where higher is better.
2026	2Hybrid	27.5	$2,700	no data	no data	0	no data
no complaint or recall data on file for 2026

How the numbers moved

Combined MPG, median2006: 19 to 2026: 27.5

Owner complaints2010: 0 to 2025: 0

How we score each year

We compare each year of the Mercedes-Benz E350 to the model's own typical numbers, not to other cars. A year reads solid when its recalls, owner complaints, and federal investigations sit at or below what is typical for this model, mixed when some of those numbers run above typical, and avoid when they run far above it. Deaths, reported fires, and an NHTSA advisory to park outside count against a year no matter what this model's baseline looks like.

A year is scored only when NHTSA has both complaint and recall counts for it. Complaint data often lags for the newest years, so a recent year can read not enough data even while its recall count already shows in the table. When the history is too thin, we say not enough data instead of guessing. Service bulletins are routine maintenance guidance from the manufacturer and do not lower a year's score.

Scores run 0 to 100, higher is better. Recall, complaint, and investigation figures come from NHTSA records. Fuel economy, fuel cost, and horsepower figures come from the EPA, shown as the median across the year's trims.

Information is gathered on a best-effort basis from public sources, may be incomplete or out of date, and is not purchasing or financial advice. Verify with the manufacturer or dealer before buying.